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In conclusion, we have developed a novel and multifunctional nano-PROTAC system that leverages in vivo self-assembly to achieve concurrent degradation of AR and HSP90, effectively overcoming resistance mechanisms in CRPC

doi: 10.3389/fonc.2021.835141 110 MinCXiu-JieSYuan-YiQSongZQing-XiaWLiqingJet al

Xu SS, Lin SZ, Lai ZX

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In this subgroup of eyes, there was statistically significant improvements in BCVA during the treatment period in cohorts 1 and 2, and statistically significant improvement in macular sensitivity was seen for cohort 3 (Supplemental Table 3), similar to what was seen for the entire population

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