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This variability may reflect differences in local microenvironmental conditions and responsiveness to treatment 46

This approach not only enhances the efficacy of herbal compounds but also significantly reduces toxicity, creating new opportunities for safer and more personalized treatment strategies

However, the chemical composition of Ganoderma is remarkably complex, and efforts are underway to broaden the research scope of its pharmacological constituents (28, 29)

Pharmacogenet Genom 35:127135

These effects were also noted after brain injury in rats with an age-dependent decreased cortical contusion volume with ketogenic neuroprotection (74)

We did not adjust for multiple comparisons when interpreting the p-values, as this is a hypothesis generating study