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This section synthesizes the principal antifibrotic mechanisms of exosomes, emphasizing their roles in cellular reprogramming, ECM regulation, and gene-level signaling modulation

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doi: 10.3389/fneur.2025.1700911 Received 07 September 2025 Revised 02 December 2025 Accepted 10 December 2025 Published 05 January 2026 Volume 16 - 2025 Edited by Paolo Taurisano, University of Bari Aldo Moro, Italy Reviewed by Nicholas Perry, Institute of Cancer Research (ICR), United Kingdom Hari Prasad Osuru, University of Virginia, United States Updates Copyright 2026 Qin and Deng