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In an early study, the use of L-asparaginase as single agent in treating ALL and lymphosarcoma was reported to achieve complete remission in some patients [81]

doi: 10.1161/CIRCRESAHA.118.313911 80 KoudstaalTvan UdenDvan HulstJACHeukelsPBergenIMGeenenLWet al
Tumors with higher SOX2 expression are more resistant to ferroptosis, and the expression of SLC7A11 is positively correlated with SOX2 in mouse and human lung cancer tissues (Wang X

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