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1 Introduction Riboflavin (vitamin B2) is a water-soluble micronutrient essential for cellular energy metabolism, antioxidant defense, and neuronal function ( Over the past decade, increasing evidence has revealed that disturbances in riboflavin metabolism, transport, or utilization contribute to a spectrum of neurological disorders

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Additionally, to the class IIa, IIb and III devices requirements, class III devices should also include indications for use, contraindications, side effects, storage conditions, etc