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In urethane-anesthetized female Wistar rats, L-theanine could reduce substance P-induced bladder hyperfunction through inhibiting pro-inflammatory protein kinase C (PKC)/ERK/NF-B/intercellular adhesion molecule 1 (ICAM-1)/IL-33 signaling, oxidative stress, apoptosis, autophagy (99)

It was also found to reduce elevated liver enzymes (ALT, AST) and reduce the progression of fibrosis in NAFLD and alcoholic liver disease (ALD)

doi: 10.1038/s41467-020-20361-3

Between 2003 and 2006, the citys economy grew in excess of 19.5% annually, the fastest in the country

& Morrow, J.D