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Paracellular and transcellular pathways maintain these functions with intestinal tight junction proteins acting as the primary regulators of paracellular permeability

When inflamed, they can become swollen, painful, and limit your ability to move freely

Proinflammatory mediators, IL (Interleukin)-1, TNF (Tumor Necrosis Factor) , and thrombin directly induce capillary tube regression

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For example, its regenerative and angiogenic effects may aid therapies involving nerve reconstruction and penile transplants of muscle or cartilage tissues