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For your body to make sufficient amounts, you also need adequate amounts of vitamin C, iron and vitamins B3 and B6
& Hakkinen, K

Research indicates that the absorption and bioavailability of LC are maximized at "small dose" supplementation, where carrier-mediated transport dominates at low concentrations, maintaining a substantial degree of linearity (Parkhouse and McKenzie 1984)

"Propionyl-L-carnitine for intermittent claudication." Cureus 2021;13:e17592

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But not all people with hypothyroidism thrive on levothyroxine alone
