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While primary TMAU is a genetic disease caused by mutations in the FMO3 gene, a transient form is also possible

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The significant decrease in arachidonic acid, octadecadienoic acid, DHA, glycerophosphate, and 3-hydroxybutyrate in cardiomyocytes indicated that L-carnitine combined with trimetazidine affected the metabolism process of lipids and promoted oxidation and metabolism of fatty acids, as well as the production of ATP, and reduced the accumulation of fatty acids and the use of 3-hydroxybutyric acid

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