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10.1146/annurev-physiol-021909-135846 63

doi: 10.1172/jci76012 47 OishiYManabeI

Bibee KP, Cheng YJ, Ching JK, et al

Patients will be excluded (1) if they have had a heart attack, stroke, hospitalization for congestive heart failure or unstable angina within 90 days before screening, (2) if they have been taking any weight loss drugs, including over-the-counter medications, within 90 days before screening, (3) if they have had a change in body weight greater than 11 pounds within 90 days, (4) if they have or are planning a surgical treatment for excess weight, (5) if they have Type 1 Diabetes Mellitus, (6) if they have a family or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN-2) and (7) if they have had pancreatitis

This might argue for an altered compartmentalization of GPX3 in IPF, e.g

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