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4 a ) had negligible senolytic activity

MMP inhibition: GHK-Cu suppresses MMP-1 (interstitial collagenase) and MMP-9 (gelatinase B) expression in cultured fibroblasts, reducing collagen degradation alongside synthesis promotion

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20 Similarly, Filardo and colleagues found that MACI treatment in osteoarthritic knees had a failure rate of 27.3% at 9-year follow-up

2020;319:F1105F1116

[DOI] [PMC free article] [PubMed] [Google Scholar] 134.Peng F, Liao M, Qin R, Zhu S, Peng C, Fu L, et al