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Studies have demonstrated that the gene gun method can decrease the necessary DNA dosage by a remarkable factor of 100 to 1,000 compared to traditional delivery methods (Nguyen-Hoai et al., 2022)

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Posa L, De Gregorio D, Gobbi G, Comai S (2018) Targeting melatonin MT2 receptors: a novel pharmacological avenue for inflammatory and neuropathic pain
