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The analysis identified 307 differentially expressed genes (DEGs) when comparing the KBiF 4 @HSA group with the PBS group, including 240 upregulated and 67 downregulated genes

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Cognitive impairment: Neuroimaging studies using PET and fMRI demonstrate reduced serotonin transporter density in the hippocampus and frontal lobes of long-term MDMA users, correlating with impaired verbal memory and executive function

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Time on ART also impacted on the AM cellular response to stress via inactivation of reactive oxygen species (ROS) and protein turnover via the unfolded protein response (UPR) ( Figure 4B )

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Acknowledgements This work was supported by the National Institute of Mental Health MH-084018 (AS), MH-094268 Silvio O

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