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The beneficial effects of mangiferin are primarily due to its antioxidant properties, as evidenced by increased levels of GPx, GST, CAT, and SOD, and its anti-inflammatory effects, indicated by decreased levels of NF-B, TNF-, IL-1, IL-6, and IL-10 [ 67 ]

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However, only 22% of the variation in MMA levels was explained by vitamin B12, estimated glomerular filtration rate, age, sex, and socioeconomic status, suggesting that other underlying disease was likely the reason for elevated MMA levels

Abstract Vitamin B12 is the common name for a group of cobalamins, which are cobalt corrines