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Because the benefits compound

The rapid onset without psychomimetic effects places it in a different category from ketamine, another fast-acting antidepressant approach that carries significant abuse potential

Unlike injectable formulations that typically require cold-chain storage, oral GLP-1RAs bypass refrigeration constraints, thereby reducing manufacturing and distribution costs and improving accessibility in resource-limited settings [73]

Huang et al., 2015), stomach (Sikiric et al., 1997a

Practical Takeaways If youre deciding between the three forms, heres how Id frame it: The mechanism of action is identical across all three