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L-propionylcarnitine effect on postexercise and postischemic hyperemia in patients affected by peripheral vascular disease

in Brunswick 89%

When oxygen availability is limited, glucose is the most metabolically efficient fuel, and during myocardial ischemia, the ratio of acetyl-CoA/CoA in mitochondria increases, leading to the activation of pyruvate dehydrogenase (PDH) kinase, which in turn phosphorylates PDH to inhibit its activity

Repeated episodes of metabolic crisis can cause brain damage

SantoSSSergioNLuigiDPGiuseppeMMargheritaFGeaOCet al
