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In cells that are stressed, there is a release of NRF2 which then is escorted from the cytoplasm into the nucleus by an importin protein, karyopherins [108]

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It is not approved for therapeutic use and is available solely for experimental and laboratory research

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Imaging of fixed samples was also performed on a Zeiss laser scanning confocal microscope LSM710 with a scanning format of 1,024 x 1,024 pixels using a 63x oil-immersion objective with 1.3 numerical aperture (NA) at equal acquisition settings within each immunostaining

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It mimics the metabolic effects of exercise by modulating circadian rhythm and boosting mitochondrial function

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Archivum Immunologiae et Therapiae Experimentalis-English Edition- 53 (3): 213

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