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The cytosolic presence of ESAT-6 is implicated in the activation of the NLRP3 inflammasome complex, including ASC and caspase-1, a process instrumental for the liberation of IL-1 ( Figure 2 ) (32)

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Sterile water lacks this preservative and must be used within 24 hours of opening, making it impractical for protocols lasting days or weeks

Cell Stress Chaperones 7 , 5564 (2002)

Other countries have a markedly lower prevalence of zinc deficiency, notably China, where its incidence decreased from 17 to 8%, as recorded in 2005 [1]

[DOI] [PubMed] [Google Scholar] [111].Degterev A, Huang Z, Boyce M, et al