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Die Ursache liegt oft in den Mitochondrien
Upon binding, PPARs can heterodimerise with retinoic acid receptor and then bind to PPAR response element, a specific DNA sequence recognised by PPARs
J Leukoc Biol (2019) 105(1):4961
The concentrations used in the experimental models often far exceeded the estimated human exposures, thus complicating the extrapolation to real-world scenarios
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Unfortunately, glutathione is depleted when toxins are detoxified and our glutathione levels decline with age
