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While the condition, called hyponatremia, is rare, it happens

Following FoxO4 knockdown, the levels of p53 and Ser15-phospho-p53 in senescent TM3 Leydig cells were further increased, but the level of p21 was decreased as compared with their control counterparts (Figure 4A4E)

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Reviews emphasize promising preclinical findings but limited robust human clinical evidence

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Independent replication in a larger, independently funded trial would significantly strengthen the evidence