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Mitophagy promotes hair cycle transition and accelerates hair regeneration by regulating the GSH metabolism that supplies energy for HG cell proliferation

Nonetheless, the forced overexpression of GPx1 has been shown to suppress cellular proliferation and migration of pancreatic cancer cells [133, 134], suggesting that GPx1 is a tumor suppressor in some cancers

While they effectively plump wrinkles, they also cause damage to hair follicles which results in hair loss

Emerging data show that VitC is also a cofactor for newly characterised hydroxylases of the family of Fe-containing 2-oxoglutarate-dependent dioxygenases that regulate gene transcription and cell signalling pathways [3, 4]

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To study these complex processes, researchers have developed a range of in vitro and in vivo models that replicate different aspects of human demyelinating disease