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For instance, PROTACs targeting BET family proteins (especially BRD4) have shown superior antitumor activity compared with corresponding inhibitors across multiple cancer models [312, 313]

3.5 Cell survival Moderate ROS promote cell survival and proliferation by means of multiple pathways, such as NF-B, MAPK, and PI3K/AKT, which play a key role in tumor drug resistance (Figure 1)

A., Varshini M

Accessed 1/8/2024, Han Y, Xie H, Liu Y, Gao P, Yang X, Shen Z

The trial showed that patients did receive higher SRS scores above what they had achieved on placebo after switching to oxytocin treatment

On the other hand, Pollini et al
