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Excessive refines carbohydrates and scarce micronutrients intakes increase inflammatory mediators nd insulin resistance in prepubertal and pubertal obese children independently of obesity

The nasal epithelium is well vascularized, and, within the olfactory area, olfactory neurons are exposed, enabling compounds transportation into the brain via the olfactory neurons [6]

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Probiotics maintain the integrity of the gut barriers integrated function and reduce intestinal permeability, which lowers endotoxin levels (226, 227)

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Lentiviral infection For lentiviral packaging, HEK293FT cells (#R70007, Invitrogen) were cultured in DMEM medium supplemented with 10% FBS and penicillin/streptomycin