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During development, NT-3 is continuously expressed in inner and outer hair cells, but only in IHCs throughout adulthood, with higher levels in the apical than basal regions

Normal biogenesis of mitochondria is triggered in response to changes in the ATP/ADP ratio and to activation of AMPK which in turn results in increased expression of PPAR co-activator 1 (PGC-1) and nuclear respiratory factor-1 (NRF1)

Commercially, this synergistic class is already limited in its adoption and use

The lncRNA, as an emerging molecular marker, exhibits unique functions in regulating gene expression and affecting the tumor microenvironment (6)

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Gastrointestinal Cancer Research 1:S37-41, 2007