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About this article Cite this article Sharma, N., Kaur, S., Kour, R

murinus ) or their beneficial metabolites (e.g., capsiate, CAT) can exert protective effects by inducing IL-10 secretion[30] or upregulating glutathione peroxidase 4 (GPX4) to inhibit ferroptosis[21]

Although rare, G6PD def Class I variants have a severe phenotype, impacting the patients quality of life [115,116]

doi: 10.1016/j.ejmech.2024.117006 119

As a master antioxidant, glutathione protects skin cells from oxidative damage caused by UV rays, pollution, and lifestyle factors

Determination of SOD activity The total activity of SOD was measured in the supernatant of heart tissue homogenate by the Cayman Chemical SOD Assay kit (USA) which utilizes a tetrazolium salt to detect the generated superoxide radicals by measuring the absorbance at 420 nm