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In vivo muscarinic cholinergic receptor imaging in human brain with [11C]scopolamine and positron emission tomography
Long-chain non-hydroxylated sulfatides were depleted, whereas shorter long-chain non-hydroxylated sulfatides were elevated in basal ganglia brain regions, including the GPi, GPe and SNR 42

Lipopolysaccharide-induced increase in intestinal epithelial tight permeability is mediated by Toll-like receptor 4/myeloid differentiation primary response 88 (Myd88) activation of myosin light chain kinase expression

Therefore, it is reasonable to assume that a parallel process of inflammation exists in both the brain and kidneys, which may mediate CKD-related cognitive decline

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