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(2022) 119:e2118300119

Data extraction and synthesis were performed iteratively, with emphasis on clinical relevance and perioperative applicability

The nuclear respiratory factor 2 (NRF2) family of transcription factors activate many genes involved in responding to oxidative stress including multiple PPP enzymes (G6PD, 6PGD, TK and TALDO) 24,25

This makes it all the more crucial to have stringent safety evaluation and oversight in place- as a means to prevent harm and to demonstrate to the public that nano-enabled foods are responsibly managed

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For instance, if GHK Cu can aid in tissue repair which includes areas like gut lining or even immune barriers that are partly structural stories as mentioned earlier, it would be interesting to see how such an approach could be beneficial in treating immune system disorders