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Plant-derived L-citrulline and L-theanine have demonstrated multifaceted benefits, primarily through mechanisms involving nitric oxide (NO) bioavailability (for L-citrulline) and mitochondrial regulation or immune modulation (for both)

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Pre-treatment telomere length and telomerase activity predicts antidepressant response We observed that TL was positively associated with Responder status after adjusting for age ( = 0.407 p = 0.007) which remained significant after further adjustment for gender, race, and smoking status ( = 0.375 p = 0.03)

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10.1152/ajpheart.00417.2015 346 YuJ