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To seek in vivo correlation, the authors assayed total glutathione in lungs and livers from MK2 (homozygous knockout) mice

In vitro studies have shown that mechanical damage to the cochlea induces transient ERK activation in SCs, which in turn triggers Ca wave oscillation in HCs 35

safety is the most important

MOI refers to the ratio of viral particles to target cells during transduction

The intracellular imaging was carried out with an FV-1000 confocal laser scanning biological microscope (Olympus, Tokyo, Japan)

Interestingly, in a nested case-control study within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort, a significant inverse association between plasma levels of betaine and colorectal cancer risk was observed only in participants with low folate concentrations [110] suggesting that choline and betaine may serve as alternative methyl group donors in states of folate deficiency