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Description
This selective receptor interaction allows localized metabolic benefits with minimal endocrine disruption, differentiating it from traditional GH analogues in research use
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"Structures of the N-terminal modules imply large domain motions during catalysis by methionine synthase"

In addition, exogenous IGF-1 administration has been shown to reduce serum glucose levels [95, 143, 144], not only in healthy individuals [140, 145147], but also in those with insulin resistance [148, 149], type I [150152], and T2D [153155]
