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Description
The exact mechanism of VHE remains unclear but is believed to be related to the accumulation of toxic VPA metabolites and elevated ammonia (NH3) levels.[4] Carnitine is an essential cofactor in the proper metabolism of VPA and NH3 elimination
However, these systemic changes in susceptible strains have not been sufficiently explored yet

doi:10.1016/j.bcp.2022.115067

[11] The trials included a total of 911 participants

Gastroenterology 133 , 13701373 (2007)

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