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doi: 10.1038/nm.3265 55 KlocMGhobrialRMLewickiSKubiakJZ
Levels of human Fis1 at the mitochondrial outer membrane regulate mitochondrial morphology
Due to gradual patient accrual and a long period for analysis and FDA submission, some patients in the pivotal trial of every-other-day 250 mcg interferon-beta 1b were followed for up to 4 to 5 years (04)
The clinical program and Phase 2b failure Phase 1 and 2a trials were successful , the peptide was safe, without significant side effects, and showed a mild lipolytic signal
The peptide does not act on the HPG axis, does not stimulate LH or FSH release, and does not bind to androgen receptors
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