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This leads us to present a scientific framework that conceptualizes Alzheimers disease (AD), Parkinsons disease (PD), amyotrophic lateral sclerosis (ALS), and Huntingtons disease (HD) as metabolic icebergs comprised of a tip, a bulk, and a base

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Mechanisms of cardioprotective effect of Withania somnifera in experimentally induced myocardial infarction

Mol Cell Biochem 396:269280 Arya A, Kumar S, Paul R, Suryavanshi A, Kain D, Sahoo RN (2021) Ethnopharmacological survey of indigenous medicinal plants of Palampur, Himachal Pradesh in north-western Himalaya, India

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By contrast, in a neurodevelopmental animal model of intellectual disability 631 , L-lactate sensing by astrocytes was reported to be increased, indicating the validity of the metabolic excitability model as a therapeutic target