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Accordingly, there have been a number of non-pharmacological interventions tailored to address underlying environmental and lifestyle risk factors that have demonstrated promising, though not conclusive, improvements in ASD symptoms [85,86]

Moreover, vitamin D is known to modulate the immune response toward a Th2 phenotype and away from the Th1 phenotype that predominates in Graves and other autoimmune diseases

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The CD38generated cADPR, in turn, augments the IFNs-induced ISGs and NF-B-mediated inflammation, leading to the antiviral hyperinflammation response