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This highlights the profound heterogeneity of Long COVID

Therefore, disturbance of any aspect of the mitochondrial energy program may disturb the development of ASD in children [29,30]

Haanes and Hkan Ashina 2025 expanded migraine therapeutics beyond CGRP, spotlighting several new biological pathways with translational promise PACAP emerged as the most advanced new target, confirmed as a CGRP-independent pathway with early preventive efficacy Substance P returned as a validated human headache trigger, reopening discussion around neurokinin-based treatments Vascular KATP channels appear to act as a convergence point for multiple migraine mediators, positioning them as a potential broad-spectrum target TRPM3 channels link trigeminal activation with sex hormone modulation, offering insight into sex differences in migraine biology PAR2 highlights neuroimmune crosstalk as a novel therapeutic direction, with preclinical antibody data showing migraine-like pain reduction Bottom line: migraine treatment is moving toward mechanism-based precision care, with multiple new targets now opening doors beyond CGRP More Cephalalgia 2025 editorials coming soon stay tuned

Extracorporeal shock wave therapy for Peyronie's disease: exploratory meta-analysis of clinical trials

doi: 10.1152/physiol.00031.2023 33

[DOI] [Google Scholar] 71.Khanmohammadi N, Movahedin M, Safari M, Sameni HR, Yousefi B, Jafari B, Zarbakhsh S
