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Human serum-derived educated spheroids were generated and cultured in hSELS medium supplemented with depleted human serum prepared according to our proprietary in-house protocol
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Fan J, Char D, Bagby GJ et al (1995) Regulation of insulin-like growth factor-I (IGF-I) and IGF-binding proteins by tumor necrosis factor
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J Pharm Pharmacol 75:rgad071 Celiska-Janowicz K, Zarba I, Lazarek U, Teul J, Tomczyk M, Paka J, Miltyk W (2018) Constituents of propolis: Chrysin, caffeic acid, p-coumaric acid, and ferulic acid induce PRODH/POX-dependent apoptosis in human tongue squamous cell carcinoma cell (CAL-27)

Overall, this trial showed that cagrilintide 0.34.5 mg for 26 weeks showed dose-dependent, clinically meaningful weight loss as an adjunct to lifestyle interventions in adults with overweight or obesity
