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This dual vulnerability exposes a therapeutic window for selectively targeting APC-mutant colorectal cancers while sparing normal epithelia

Cell death via mitochondrial apoptotic pathway due to activation of Bax by lysosomal photodamage

In MPTP-treated animals, phenylbutyrate protected DA neurons in the SNpc and increase DJ-1 expression (Gardian et al., 2004

Fluorescence intensity was quantified using the Zeiss ZEN software package

Furthermore, we proposed a comprehensive mechanism of action for stem cell secretions, encompassing the broader secretome as well as the specific contribution of exosomes, in alleviating ASD neuropathology
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