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Box maze results after 12 weeks, when mice were 7 months of age, showed that transgenic mice treated with intranasal GHK-Cu had reduced escape latencies compared to transgenic mice treated with intranasal saline, reflecting decreased escape times over three trials and indicating improved learning capacity (Figure 2A and B)

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CDS: 128-1327) SEQ ID NO: 8human VSIG4 isoform 1 amino acid sequence (NP-009199.1) SEQ ID NO: 9 humanVSIG4 transcript variant 2 cDNA sequence (NM-001100431.1