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Description
It forms adducts with various cellular components
Hassing L, Wahlin A, Winblad B, Backman L
Crizotinib, an ALK/ROS1/MET inhibitor, is an FDA-approved targeted agent for the treatment of advanced ROS1-rearranged NSCLC, and studies have shown that some ALK TKIs have dual inhibitory activity against ALK and ROS1 [44]
doi: 10.1097/WNR.0000000000001648 72
doi: 10.1038/s41467-018-03421-7
(2024) clinical study revealed significantly increased levels of LP markers, such as MDA and F2-isoprostanes, in patients with severe anxiety
