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Many inhibitors also have off-target effects, which become more pronounced at high concentrations

Finally, we calculated the F statistics before MR analysis, and all SNPs were greater than 10, suggesting the strong instruments of IVs (37)

doi: 10.1182/blood.2023020814 122 TeacheyDTRheingoldSRMaudeSLZugmaierGBarrettDMSeifAEet al

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Kidney failure can be caused by injuries, chronic health conditions, or unknown reasons

doi: 10.3389/fmed.2025.1549658 Received 21 December 2024 Accepted 11 March 2025 Published 26 March 2025 Volume 12 - 2025 Edited by Matteo Becatti, University of Firenze, Italy Reviewed by Laura Vitiello, IRCCS San Raffaele Roma, Italy Francesca Nencini, University of Florence, Italy Updates Copyright 2025 Mao, Liu, Fan, Zhang, Liu and Xiao