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doi: 10.1093/infdis/jiz643 76 KumagaiTPalaciosACasadevallAGarcaMJToroCTiemeyerMet al

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Future research should focus on elucidating the specific mechanisms of hormone-MBOAT1/2 interactions in OA treatment and further validating their clinical applications in personalized therapies

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Using aseptic technique, withdraw the appropriate dose (650 mg or weight-based) from an intact sealed Acetaminophen Injection container and place the measured dose in a separate empty, sterile container (e.g., glass bottle, plastic intravenous container, or syringe) for intravenous infusion to avoid the inadvertent delivery and administration of the total volume of the commercially available container

The release of excess iron during CNS demyelination is potentially directly neurotoxic due to increased extracellular concentrations of unbuffered ferrous iron in the form of divalent cations (Fe 2+ ), which amplifies oxidative injury via the Fenton reaction [171]