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NAC and glycine have been shown to maintain healthy cytokine release during times of metabolic stress

Neonatal opioid withdrawal syndrome presents as irritability, hyperactivity, abnormal sleep pattern, high pitched cry, tremor, vomiting, diarrhea and failure to gain weight

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Another study reported germ cell sloughing, necrosis, and damage to seminiferous tubules in 4-week-old rats, which led to a Sertoli cell-only phenotype when exposed to DZN at sub-chronic doses for 90 days via drinking water [37]

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Considering the fundamental importance of glutamate in various brain functions and the inherent complexity of behavior, it becomes evident that alterations in glutamatergic signaling, depending on the exposure window, duration, and magnitude, can lead to distinct and detectable behavioral outcomes