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Aside from genetics, another factor that can contribute to hollow cheeks is aging

doi: 10.1016/j.rpth.2023.100570 10 JoshiSSmithAAlfarHRPrakhyaKSChanzuHWhiteheartSWet al

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doi: 10.1038/sj.jid.5700327
Moreover, Cys26 from the N-terminal segment and Cys584 from the IPT1 domain are closely adjacent to each other in our model, suggesting that they form a disulfide bond to further strengthen the interaction between these two structural motifs (Supplementary Fig
