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These portable coolers maintain temperatures between 2 and 8 degrees Celsius for 12 to 24 hours depending on the ambient temperature and insulation quality

Golombek SK, May JN, Theek B, Appold L, Drude N, Kiessling F, Lammers T (2018) Tumor targeting via EPR: strategies to enhance patient responses

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In contrast, mid-lateral injuries do generate a developing contusion core (Vink et al., 2001)
