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The plate was transferred to a fluorescence-compatible plate reader maintained at 37 C to measure the change in NADPH autofluorescence every minute over a period of 45 min
These data, together with mechanistic work showing that insulin stimulates VEGF and IGF production while glucose primes macrophages for inflammatory cytokine release 394 , suggest that the combination of high glucose and high insulin is more deleterious than hyperglycemia alone
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Nausea is one of the side effects some patients may experience, and it usually disappears when the body becomes accustomed to the treatment
U-RBCs could also have other benefits
