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Characterization of a common VIP-PACAP receptor in human small intestinal epithelium

Pernicious Anaemia Society 2019 Conference

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To test the impact of our compounds on native and neosubstrate levels in a cell-based system, we treated HEK293T cells with UNC10415667 or UNC12567, a structurally similar inactive degrader that cannot bind NSD2 (10 M for 6 hrs)

Advances across lipid-based carriers, biodegradable polymers, inorganic nanostructures, and biomimetic systems have expanded the therapeutic landscape, supporting the delivery of antivirals, immunomodulators, and gene-editing tools