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Most importantly, numerous other neuroprotective and neurotrophic growth factors like BDNF-analogs and LM11A-31 are currently being studied for their cognitive and therapeutic benefits, especially their ability to preserve and promote neural networks and neuron health, particularly in the setting of neurodegenerative diseases like Alzheimer's disease, FrontoTemporal Dementia (FTD), Parkinson's Disease (PD), and Lewy-Body Disease, as well as ischemic or traumatic neural injury (68a) (68b) (68c) (68d)

While the sensory vagus nerve and ENS are intrinsically linked, the mechanisms underpinning this interaction and the role of vagal signalling from the ENS to the brain remain incompletely understood

Glossary NADase An enzymatic activity that leads to the degradation of NAD unrespect of the products NAD glycohydrolase The break of the glycosidic bond between nicotinamide and ribose of NAD

10.1016/S0304-3940(03)00558-5 257 SilesA

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Zamia, N