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SCHEME 1 2 The roles of overexpressed GSH in cancer cells Cancer is characterized by the fast and uncontrolled proliferation of abnormal cells in the body

Growth hormone-binding protein in human lymph

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We will break down each approach in detail throughout this article

The overproduction of lactate would thus be secreted into the circulation through MCT4 and preferentially bind to GPR81 on endothelial cells, to reduce endothelial VE-Cadherin expression and increase vascular permeability through different signaling

*Correspondence: Do-Hee Kim, [email protected] This article was submitted to Cancer Metabolism, a section of the journal Frontiers in Oncology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers