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Description
The only legitimate way to access these medicines in the UK is through participation in a registered clinical trial, which can be found via NIHR Be Part of Research or ClinicalTrials.gov
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GS, a key enzyme of de novo Gln synthesis, is downregulated in PCa tissues compared to non-malignant prostate epithelia [122]
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On the one hand, IL-1 exacerbates BBB disruption by downregulating tight junction protein Zonula Oc-cludens-1 (ZO-1), activating caspase-1 within the brain, and establishing a positive feedback loop that amplifies IL-1 production (36)
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