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In multiple sclerosis (MS), disturbed lipid homeostasis affects myelin synthesis and oligodendrocyte function, while lipid mediators such as eicosanoids and sphingolipids modulate immune responses and neuroinflammation (Lpez-Muguruza and Matute, 2023)
Given that improvement in social deficits is observed following relatively short-term MT-II treatment, this is likely mediated by neuromodulatory signaling downstream of MC4R including increased oxytocin activity that overrides existing asocial structural abnormalities
It functions by transporting long-chain fatty acids into the mitochondria the powerhouses of cells where they are oxidized to produce energy
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
Right place, right time: localisation and assembly of the NLRP3 inflammasome
Decreased release of lipoprotein lipase is associated with vascular endothelial damage in NIDDM patients with microalbuminuria
